Studies on the extended spectrum beta lactamases activity in isolates from diabetes patients

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Studies on the extended spectrum beta lactamases activity in isolates from diabetes patients

Background Extended spectrum beta-lactamases (ESBLs) are enzymes produced by some gram negative bacilli that mediate resistance to extended-spectrum cephalosporins and aztreonam. ESBLs are commonly recognized in a variety of Enterobacteriaceae and Pseudomonas aeruginosa isolates. This study focused on the prevalence of ESBL producing strains from diabetes patients and their antimicrobial correl...

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Detection of Ampc and Extended-Spectrum Beta-Lactamases in Clinical Isolates of Pseudomonas Aeruginosa from Patients with Cystic Fibrosis

ABSTRACT        Background and Objectives: Pseudomonas aeruginosa is the most frequent opportunistic pathogen isolated from the sputum of patients with cystic fibrosis (CF). Resistance to β -lactam antibiotics may arise from over expression of the naturally occurring AmpC cephalosporinases or acquired extended-spectrum β-lactamases (ESBL). The aim of...

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Extended - spectrum Beta - lactamases

Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...

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Extended-spectrum beta-lactamases.

At least 30 extended-spectrum beta-lactamases (ESB) have emerged responsible for resistance to indigestible beta-lactams (C3G) since their discovery in West Germany in 1983. Most of them are produced by enterobacteria and essentially K. pneumoniae which appeared susceptible to oxyimino-beta-lactams. A double-disk test was useful to detect such nosocomial isolates of enterobacteria (urines, bloo...

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Frequency of E. coli clinical isolates producing blaSHV and blaTEM extended-spectrum beta-lactamases

Introduction: Production of extended-spectrum beta-lactamase enzymes (ESBLs) in E. coli creates many problems for patients. These enzymes are located on transferable elements and can hydrolyze penicillins, broad-spectrum cephalosporins, and aztreonam. This study aimed to determine the clinical isolates of E. coli producing ESBLs of blaSHV and blaTEM in the city of Zanjan. Methods: This cross...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2012

ISSN: 1471-2334

DOI: 10.1186/1471-2334-12-s1-p86